7vzg
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c (the larger form)== | |
| + | <StructureSection load='7vzg' size='340' side='right'caption='[[7vzg]], [[Resolution|resolution]] 2.61Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7vzg]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Chloracidobacterium_thermophilum Chloracidobacterium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VZG FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2GO:[methyl+9-acetyl-14-ethyl-20-hydroxy-4,8,13,18-tetramethyl-3-{3-oxo-3-[(3,7,11,15-tetramethylhexadec-2-en-1-yl)oxy]propyl}-3,4,20,21-tetradehydrophorbine-21-carboxylatato(2-)-kappa~4~N~23~,N~24~,N~25~,N~26~]zinc'>2GO</scene>, <scene name='pdbligand=84Q:[(2S)-2-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-2-(13-methyltetradecanoyloxy)ethyl]+13-methyltetradecanoate'>84Q</scene>, <scene name='pdbligand=85I:[(2~{R})-2-[2-(methylamino)ethoxy-oxidanyl-phosphoryl]oxy-2-(13-methyltetradecanoyloxy)ethyl]+13-methyltetradecanoate'>85I</scene>, <scene name='pdbligand=85N:[(2~{S})-2-[[(1~{R})-1,2-bis(13-methyltetradecanoyloxy)ethoxy]methyl]-3-oxidanyl-3-oxidanylidene-propyl]-trimethyl-azanium'>85N</scene>, <scene name='pdbligand=BCL:BACTERIOCHLOROPHYLL+A'>BCL</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CLA:CHLOROPHYLL+A'>CLA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=LYC:LYCOPENE'>LYC</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vzg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vzg OCA], [https://pdbe.org/7vzg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vzg RCSB], [https://www.ebi.ac.uk/pdbsum/7vzg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vzg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/G2LDR4_CHLTF G2LDR4_CHLTF] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Photosynthesis converts light energy to chemical energy to fuel life on earth. Light energy is harvested by antenna pigments and transferred to reaction centers (RCs) to drive the electron transfer (ET) reactions. Here, we present cryo-electron microscopy (cryo-EM) structures of two forms of the RC from the microaerophilic Chloracidobacterium thermophilum (CabRC): one containing 10 subunits, including two different cytochromes; and the other possessing two additional subunits, PscB and PscZ. The larger form contained 2 Zn-bacteriochlorophylls, 16 bacteriochlorophylls, 10 chlorophylls, 2 lycopenes, 2 hemes, 3 Fe(4)S(4) clusters, 12 lipids, 2 Ca(2+) ions and 6 water molecules, revealing a type I RC with an ET chain involving two hemes and a hybrid antenna containing bacteriochlorophylls and chlorophylls. Our results provide a structural basis for understanding the excitation energy and ET within the CabRC and offer evolutionary insights into the origin and adaptation of photosynthetic RCs. | ||
| - | + | Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c.,Dong S, Huang G, Wang C, Wang J, Sui SF, Qin X Nat Commun. 2022 Dec 14;13(1):7745. doi: 10.1038/s41467-022-35460-6. PMID:36517472<ref>PMID:36517472</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 7vzg" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chloracidobacterium thermophilum]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Dong SS]] | ||
| + | [[Category: Huang GQ]] | ||
| + | [[Category: Qin XC]] | ||
| + | [[Category: Sui SF]] | ||
Revision as of 12:32, 22 February 2023
Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c (the larger form)
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