8alq
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2 that Binds to Asymmetrically Modified DNA== | |
| - | + | <StructureSection load='8alq' size='340' side='right'caption='[[8alq]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8alq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ALQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ALQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8alq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8alq OCA], [https://pdbe.org/8alq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8alq RCSB], [https://www.ebi.ac.uk/pdbsum/8alq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8alq ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: Singh | + | == Function == |
| + | [https://www.uniprot.org/uniprot/A0A8C5LDB3_JACJA A0A8C5LDB3_JACJA] Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).[PIRNR:PIRNR038006] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Singh H]] | ||
Revision as of 12:39, 22 February 2023
The Solution Structure of the Triple Mutant Methyl-CpG-Binding Domain from MeCP2 that Binds to Asymmetrically Modified DNA
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