8egx
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Complex of Fat4(EC1-4) bound to Dchs1(EC1-4)== | |
| - | + | <StructureSection load='8egx' size='340' side='right'caption='[[8egx]], [[Resolution|resolution]] 3.69Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8egx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EGX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8egx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8egx OCA], [https://pdbe.org/8egx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8egx RCSB], [https://www.ebi.ac.uk/pdbsum/8egx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8egx ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/FAT4_HUMAN FAT4_HUMAN] Hennekam syndrome;Cerebrofacioarticular syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FAT4_HUMAN FAT4_HUMAN] Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Luca VC]] | ||
| + | [[Category: Medina E]] | ||
Revision as of 12:43, 22 February 2023
Complex of Fat4(EC1-4) bound to Dchs1(EC1-4)
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