7yxa
From Proteopedia
(Difference between revisions)
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<StructureSection load='7yxa' size='340' side='right'caption='[[7yxa]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='7yxa' size='340' side='right'caption='[[7yxa]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[7yxa]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YXA FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7yxa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YXA FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B2O:4-[6-(2-naphthalen-1-ylethoxy)-2,3,4,5-tetrahydro-1H-3-benzazepin-3-ium-3-yl]butanoic+acid'>B2O</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B2O:4-[6-(2-naphthalen-1-ylethoxy)-2,3,4,5-tetrahydro-1H-3-benzazepin-3-ium-3-yl]butanoic+acid'>B2O</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yxa OCA], [https://pdbe.org/7yxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yxa RCSB], [https://www.ebi.ac.uk/pdbsum/7yxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yxa ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yxa OCA], [https://pdbe.org/7yxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yxa RCSB], [https://www.ebi.ac.uk/pdbsum/7yxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yxa ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[https://www.uniprot.org/uniprot/S1PR5_HUMAN S1PR5_HUMAN | + | [https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.[https://www.uniprot.org/uniprot/S1PR5_HUMAN S1PR5_HUMAN] Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Borshchevskiy | + | [[Category: Borshchevskiy V]] |
| - | [[Category: Bourenkov | + | [[Category: Bourenkov G]] |
| - | [[Category: Bukhdruker | + | [[Category: Bukhdruker S]] |
| - | [[Category: Cherezov | + | [[Category: Cherezov V]] |
| - | [[Category: Cho | + | [[Category: Cho Y]] |
| - | [[Category: Ergasheva | + | [[Category: Ergasheva M]] |
| - | [[Category: Gerasimov | + | [[Category: Gerasimov A]] |
| - | [[Category: Gordeliy | + | [[Category: Gordeliy V]] |
| - | [[Category: Gusach | + | [[Category: Gusach A]] |
| - | [[Category: Gushchin | + | [[Category: Gushchin I]] |
| - | [[Category: Hu | + | [[Category: Hu H]] |
| - | [[Category: Huyn | + | [[Category: Huyn HJ]] |
| - | [[Category: Khorn | + | [[Category: Khorn P]] |
| - | [[Category: Khusainov | + | [[Category: Khusainov G]] |
| - | [[Category: Kovalev | + | [[Category: Kovalev K]] |
| - | [[Category: Kovaleva | + | [[Category: Kovaleva M]] |
| - | [[Category: Liu | + | [[Category: Liu W]] |
| - | [[Category: Luginina | + | [[Category: Luginina A]] |
| - | [[Category: Lyapina | + | [[Category: Lyapina E]] |
| - | [[Category: Marin | + | [[Category: Marin E]] |
| - | [[Category: Mishin | + | [[Category: Mishin A]] |
| - | [[Category: Okhrimenko | + | [[Category: Okhrimenko I]] |
| - | [[Category: Orekhov | + | [[Category: Orekhov P]] |
| - | [[Category: Park | + | [[Category: Park G]] |
| - | [[Category: Park | + | [[Category: Park J]] |
| - | [[Category: Park | + | [[Category: Park S]] |
| - | [[Category: Popov | + | [[Category: Popov P]] |
| - | [[Category: Rogachev | + | [[Category: Rogachev A]] |
| - | [[Category: Shevtsov | + | [[Category: Shevtsov M]] |
| - | [[Category: Vakhrameev | + | [[Category: Vakhrameev D]] |
| - | [[Category: Weierstall | + | [[Category: Weierstall U]] |
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Revision as of 12:54, 22 February 2023
XFEL crystal structure of the human sphingosine 1 phosphate receptor 5 in complex with ONO-5430608
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Categories: Homo sapiens | Large Structures | Borshchevskiy V | Bourenkov G | Bukhdruker S | Cherezov V | Cho Y | Ergasheva M | Gerasimov A | Gordeliy V | Gusach A | Gushchin I | Hu H | Huyn HJ | Khorn P | Khusainov G | Kovalev K | Kovaleva M | Liu W | Luginina A | Lyapina E | Marin E | Mishin A | Okhrimenko I | Orekhov P | Park G | Park J | Park S | Popov P | Rogachev A | Shevtsov M | Vakhrameev D | Weierstall U
