This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1jzn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1jzn.gif|left|200px]]
[[Image:1jzn.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1jzn |SIZE=350|CAPTION= <scene name='initialview01'>1jzn</scene>, resolution 2.20&Aring;
+
The line below this paragraph, containing "STRUCTURE_1jzn", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLC:GLUCOSE'>GLC</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1jzn| PDB=1jzn | SCENE= }}
-
|RELATEDENTRY=[[1muq|1MUQ]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jzn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jzn OCA], [http://www.ebi.ac.uk/pdbsum/1jzn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1jzn RCSB]</span>
+
-
}}
+
'''crystal structure of a galactose-specific C-type lectin'''
'''crystal structure of a galactose-specific C-type lectin'''
Line 30: Line 27:
[[Category: Walker, J R.]]
[[Category: Walker, J R.]]
[[Category: Young, N M.]]
[[Category: Young, N M.]]
-
[[Category: c-type lectin]]
+
[[Category: C-type lectin]]
-
[[Category: protein-disaccharide complex]]
+
[[Category: Protein-disaccharide complex]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:07:02 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:41:16 2008''
+

Revision as of 19:07, 2 May 2008

Image:1jzn.gif

Template:STRUCTURE 1jzn

crystal structure of a galactose-specific C-type lectin


Overview

Rattlesnake venom lectin (RSL) from the western diamondback rattlesnake (Crotalus atrox) is an oligomeric galactose-specific C-type lectin. The X-ray crystal structure of RSL, in complex with lactose and thiodigalactoside, at 2.2 and 2.3 A resolution, respectively, reveals a decameric protein composed of two 5-fold symmetric pentamers arranged in a staggered, back-to-back orientation. Each monomer corresponds to a single canonical C-type lectin carbohydrate recognition domain devoid of accessory domains and is disulfide-bonded to a monomer in the other pentamer. The structure is the first example of that of a carbohydrate complex of a vertebrate galactose-specific C-type lectin. The 10 carbohydrate-binding sites, located on the rim of the decamer, suggest a role for multivalent interactions and a mechanism for RSL's ability to promote receptor cross-linking and cell aggregation.

About this Structure

1JZN is a Single protein structure of sequence from Crotalus atrox. Full crystallographic information is available from OCA.

Reference

X-ray crystal structure of a galactose-specific C-type lectin possessing a novel decameric quaternary structure., Walker JR, Nagar B, Young NM, Hirama T, Rini JM, Biochemistry. 2004 Apr 6;43(13):3783-92. PMID:15049685 Page seeded by OCA on Fri May 2 22:07:02 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1jzn"
Personal tools