2m0c

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==Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C==
==Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C==
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<StructureSection load='2m0c' size='340' side='right'caption='[[2m0c]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2m0c' size='340' side='right'caption='[[2m0c]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2m0c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2m0c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0C FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ALX4, KIAA1788 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0c OCA], [https://pdbe.org/2m0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0c RCSB], [https://www.ebi.ac.uk/pdbsum/2m0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0c OCA], [https://pdbe.org/2m0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0c RCSB], [https://www.ebi.ac.uk/pdbsum/2m0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0c ProSAT]</span></td></tr>
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</table>
</table>
== Disease ==
== Disease ==
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[[https://www.uniprot.org/uniprot/ALX4_HUMAN ALX4_HUMAN]] Isolated scaphocephaly;Parietal foramina;Frontonasal dysplasia with alopecia and genital anomaly;Potocki-Shaffer syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Disease susceptibility is associated with variations affecting the gene represented in this entry.
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[https://www.uniprot.org/uniprot/ALX4_HUMAN ALX4_HUMAN] Isolated scaphocephaly;Parietal foramina;Frontonasal dysplasia with alopecia and genital anomaly;Potocki-Shaffer syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Disease susceptibility is associated with variations affecting the gene represented in this entry.
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ALX4_HUMAN ALX4_HUMAN]] Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development.<ref>PMID:19692347</ref>
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[https://www.uniprot.org/uniprot/ALX4_HUMAN ALX4_HUMAN] Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development.<ref>PMID:19692347</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Acton, T B]]
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[[Category: Acton TB]]
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[[Category: Eletsky, A]]
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[[Category: Eletsky A]]
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[[Category: Everett, J K]]
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[[Category: Everett JK]]
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[[Category: Janjua, H]]
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[[Category: Janjua H]]
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[[Category: Lee, D]]
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[[Category: Lee D]]
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[[Category: Montelione, G T]]
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[[Category: Montelione GT]]
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[[Category: Structural genomic]]
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[[Category: Pulavarti S]]
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[[Category: Pulavarti, S]]
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[[Category: Szyperski T]]
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[[Category: Szyperski, T]]
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[[Category: Xiao R]]
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[[Category: Xiao, R]]
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[[Category: Xu X]]
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[[Category: Xu, X]]
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[[Category: Gene regulation]]
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[[Category: Nesg]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi-biology]]
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Revision as of 13:22, 22 February 2023

Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C

PDB ID 2m0c

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