2m10
From Proteopedia
(Difference between revisions)
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==trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative== | ==trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative== | ||
| - | <StructureSection load='2m10' size='340' side='right'caption='[[2m10 | + | <StructureSection load='2m10' size='340' side='right'caption='[[2m10]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2m10]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2m10]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M10 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=33B:3,3-(E)-DIAZENE-1,2-DIYLBIS{6-[(CHLOROACETYL)AMINO]BENZENESULFONIC+ACID}'>33B</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=33B:3,3-(E)-DIAZENE-1,2-DIYLBIS{6-[(CHLOROACETYL)AMINO]BENZENESULFONIC+ACID}'>33B</scene></td></tr> | ||
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2m0z|2m0z]]</div></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPN13, PNP1, PTP1E, PTPL1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m10 OCA], [https://pdbe.org/2m10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m10 RCSB], [https://www.ebi.ac.uk/pdbsum/2m10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m10 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m10 OCA], [https://pdbe.org/2m10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m10 RCSB], [https://www.ebi.ac.uk/pdbsum/2m10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m10 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PTN13_HUMAN PTN13_HUMAN] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.<ref>PMID:15611135</ref> | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Walser R]] | |
| - | [[Category: Walser | + | |
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Current revision
trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative
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