2m52

<StructureSection load='2m52' size='340' side='right'caption='[[2m52]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>

<table><tr><td colspan='2'>[[2m52]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M52 FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1o0p|1o0p]], [[1opi|1opi]], [[2m0g|2m0g]], [[3v4m|3v4m]], [[4fxw|4fxw]]</div></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m52 OCA], [https://pdbe.org/2m52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m52 RCSB], [https://www.ebi.ac.uk/pdbsum/2m52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m52 ProSAT]</span></td></tr>

[[https://www.uniprot.org/uniprot/U2AF2_MOUSE U2AF2_MOUSE]] Necessary for the splicing of pre-mRNA. Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10 (By similarity).

[[Category: Lk3 transgenic mice]]

[[Category: Dutta, S K]]

[[Category: Geralt, M]]

[[Category: Structural genomic]]

[[Category: Serrano, P]]

[[Category: TCELL, Partnership for T-Cell Biology]]

[[Category: Wuthrich, K]]

[[Category: Tcell]]