2m5h

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==NMR structure note: solution structure of monomeric human FAM96A==
==NMR structure note: solution structure of monomeric human FAM96A==
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<StructureSection load='2m5h' size='340' side='right'caption='[[2m5h]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2m5h' size='340' side='right'caption='[[2m5h]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2m5h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M5H FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2m5h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M5H FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FAM96A ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m5h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5h OCA], [https://pdbe.org/2m5h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m5h RCSB], [https://www.ebi.ac.uk/pdbsum/2m5h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5h ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m5h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5h OCA], [https://pdbe.org/2m5h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m5h RCSB], [https://www.ebi.ac.uk/pdbsum/2m5h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5h ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/FA96A_HUMAN FA96A_HUMAN]] May play a role in chromosome segregation through establishment of sister chromatid cohesion (By similarity).
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[https://www.uniprot.org/uniprot/CIA2A_HUMAN CIA2A_HUMAN] Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227).<ref>PMID:23891004</ref> <ref>PMID:25716227</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ouyang, B]]
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[[Category: Ouyang B]]
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[[Category: Xia, B]]
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[[Category: Xia B]]
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[[Category: 3d domain swapping]]
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[[Category: Duf59]]
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[[Category: Fam96a]]
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[[Category: Immune system]]
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Revision as of 13:30, 22 February 2023

NMR structure note: solution structure of monomeric human FAM96A

PDB ID 2m5h

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