4qo3

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<StructureSection load='4qo3' size='340' side='right'caption='[[4qo3]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='4qo3' size='340' side='right'caption='[[4qo3]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qo3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QO3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qo3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QO3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2afg|2afg]], [[1jqz|1jqz]], [[1rg8|1rg8]], [[4q91|4q91]], [[4q9g|4q9g]], [[4q9p|4q9p]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qo3 OCA], [https://pdbe.org/4qo3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qo3 RCSB], [https://www.ebi.ac.uk/pdbsum/4qo3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qo3 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FGF1, FGFA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qo3 OCA], [http://pdbe.org/4qo3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qo3 RCSB], [http://www.ebi.ac.uk/pdbsum/4qo3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qo3 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN]] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref>
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[https://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref>
==See Also==
==See Also==
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*[[Fibroblast growth factor|Fibroblast growth factor]]
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*[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Blaber, M]]
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[[Category: Blaber M]]
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[[Category: Xia, X]]
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[[Category: Xia X]]
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[[Category: Beta-trefoil]]
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[[Category: Fgfr binding]]
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[[Category: Growth factor]]
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[[Category: Heparin binding]]
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[[Category: Protein binding]]
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Revision as of 13:43, 22 February 2023

Crystal structure of C16S/N18S/K12V/C117V/P134V mutant of human acidic fibroblast growth factor

PDB ID 4qo3

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