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4qqr

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<StructureSection load='4qqr' size='340' side='right'caption='[[4qqr]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4qqr' size='340' side='right'caption='[[4qqr]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qqr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QQR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qqr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QQR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QQR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">At1g63000, ER, F16P17.17, NRS, NRS/ER ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqr OCA], [https://pdbe.org/4qqr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qqr RCSB], [https://www.ebi.ac.uk/pdbsum/4qqr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qqr ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qqr OCA], [http://pdbe.org/4qqr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qqr RCSB], [http://www.ebi.ac.uk/pdbsum/4qqr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qqr ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RMLCD_ARATH RMLCD_ARATH]] Bifunctional enzyme involved in dTDP-beta-L-rhamnose biosynthesis. Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-4-keto-alpha-D-glucose to form dTDP-4-keto-beta-L-rhamnose and its reduction to yield dTDP-beta-L-rhamnose. Can form UDP-beta-L-rhamnose from UDP-6-deoxy-4-keto-alpha-D-glucose, but cannot convert GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose.<ref>PMID:15020741</ref>
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[https://www.uniprot.org/uniprot/RMLCD_ARATH RMLCD_ARATH] Bifunctional enzyme involved in dTDP-beta-L-rhamnose biosynthesis. Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-4-keto-alpha-D-glucose to form dTDP-4-keto-beta-L-rhamnose and its reduction to yield dTDP-beta-L-rhamnose. Can form UDP-beta-L-rhamnose from UDP-6-deoxy-4-keto-alpha-D-glucose, but cannot convert GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose.<ref>PMID:15020741</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arath]]
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[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Han, X]]
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[[Category: Han X]]
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[[Category: Liu, X]]
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[[Category: Liu X]]
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[[Category: Beta barrel]]
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[[Category: Epimerase-reductase]]
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[[Category: Oxidoreductase]]
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[[Category: Rossmann fold]]
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Revision as of 13:47, 22 February 2023

Structural insight into nucleotide rhamnose synthase/epimerase-reductase from Arabidopsis thaliana

PDB ID 4qqr

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