2m96
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Solution NMR structure of the RXFP2 LDLa module== | ==Solution NMR structure of the RXFP2 LDLa module== | ||
| - | <StructureSection load='2m96' size='340' side='right'caption='[[2m96 | + | <StructureSection load='2m96' size='340' side='right'caption='[[2m96]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2m96]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2m96]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M96 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RXFP2, GPR106, GREAT, LGR8 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m96 OCA], [https://pdbe.org/2m96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m96 RCSB], [https://www.ebi.ac.uk/pdbsum/2m96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m96 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m96 OCA], [https://pdbe.org/2m96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m96 RCSB], [https://www.ebi.ac.uk/pdbsum/2m96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m96 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | + | [https://www.uniprot.org/uniprot/RXFP2_HUMAN RXFP2_HUMAN] The disease is caused by mutations affecting the gene represented in this entry. | |
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/RXFP2_HUMAN RXFP2_HUMAN] Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). | |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bathgate | + | [[Category: Bathgate AD]] |
| - | [[Category: Gooley | + | [[Category: Gooley PR]] |
| - | [[Category: Petrie | + | [[Category: Petrie EJ]] |
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 06:28, 2 March 2023
Solution NMR structure of the RXFP2 LDLa module
| |||||||||||
