2mdx

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==Solution structure of the human wild type FAPP1-PH domain==
==Solution structure of the human wild type FAPP1-PH domain==
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<StructureSection load='2mdx' size='340' side='right'caption='[[2mdx]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2mdx' size='340' side='right'caption='[[2mdx]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2mdx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2mdx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDX FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2kcj|2kcj]], [[3rcp|3rcp]]</div></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdx OCA], [https://pdbe.org/2mdx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdx RCSB], [https://www.ebi.ac.uk/pdbsum/2mdx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdx ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PLEKHA3, FAPP1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdx OCA], [https://pdbe.org/2mdx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdx RCSB], [https://www.ebi.ac.uk/pdbsum/2mdx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdx ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PKHA3_HUMAN PKHA3_HUMAN]] Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4-phosphate (PtdIns4P).<ref>PMID:15107860</ref>
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[https://www.uniprot.org/uniprot/PKHA3_HUMAN PKHA3_HUMAN] Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4-phosphate (PtdIns4P).<ref>PMID:15107860</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lenoir, M]]
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[[Category: Lenoir M]]
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[[Category: Overduin, M]]
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[[Category: Overduin M]]
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[[Category: Membrane protein]]
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[[Category: Phosphoinositide]]
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[[Category: Pleckstrin homology]]
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Revision as of 06:32, 2 March 2023

Solution structure of the human wild type FAPP1-PH domain

PDB ID 2mdx

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