4r9u

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<StructureSection load='4r9u' size='340' side='right'caption='[[4r9u]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
<StructureSection load='4r9u' size='340' side='right'caption='[[4r9u]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4r9u]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R9U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R9U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4r9u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R9U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">btuC, b1711, JW1701 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), btuD, b1709, JW1699 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r9u OCA], [https://pdbe.org/4r9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r9u RCSB], [https://www.ebi.ac.uk/pdbsum/4r9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r9u ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Vitamin_B12-transporting_ATPase Vitamin B12-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.33 3.6.3.33] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r9u OCA], [http://pdbe.org/4r9u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r9u RCSB], [http://www.ebi.ac.uk/pdbsum/4r9u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r9u ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BTUC_ECOLI BTUC_ECOLI]] Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.[HAMAP-Rule:MF_01004] [[http://www.uniprot.org/uniprot/BTUD_ECOLI BTUD_ECOLI]] Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity).
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[https://www.uniprot.org/uniprot/BTUC_ECOLI BTUC_ECOLI] Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.[HAMAP-Rule:MF_01004]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Vitamin B12-transporting ATPase]]
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[[Category: Korkhov VM]]
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[[Category: Korkhov, V M]]
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[[Category: Locher KP]]
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[[Category: Locher, K P]]
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[[Category: Mireku SA]]
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[[Category: Mireku, S A]]
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[[Category: Veprintsev DB]]
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[[Category: Veprintsev, D B]]
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[[Category: Abc transporter]]
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[[Category: Amppnp]]
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[[Category: Atp binding cassette]]
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[[Category: Btuf]]
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[[Category: Hydrolase]]
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[[Category: Inner membrane]]
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[[Category: Membrane protein]]
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[[Category: Nucleotide]]
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Revision as of 06:46, 2 March 2023

Structure of vitamin B12 transporter BtuCD in a nucleotide-bound outward facing state

PDB ID 4r9u

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