4ram
From Proteopedia
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| <StructureSection load='4ram' size='340' side='right'caption='[[4ram]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='4ram' size='340' side='right'caption='[[4ram]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
| == Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ram]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4ram]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RAM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RAM FirstGlance]. <br> | 
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PNM:OPEN+FORM+-+PENICILLIN+G'>PNM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PNM:OPEN+FORM+-+PENICILLIN+G'>PNM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | 
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ram FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ram OCA], [https://pdbe.org/4ram PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ram RCSB], [https://www.ebi.ac.uk/pdbsum/4ram PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ram ProSAT]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
| </table> | </table> | ||
| == Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | 
| ==See Also== | ==See Also== | ||
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| __TOC__ | __TOC__ | ||
| </StructureSection> | </StructureSection> | ||
| - | [[Category:  | + | [[Category: Klebsiella pneumoniae]] | 
| [[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Babnigg | + | [[Category: Babnigg G]] | 
| - | [[Category: Jedrzejczak | + | [[Category: Jedrzejczak R]] | 
| - | [[Category: Joachimiak | + | [[Category: Joachimiak A]] | 
| - | [[Category: Kim | + | [[Category: Kim Y]] | 
| - | + | [[Category: Sacchettini J]] | |
| - | + | [[Category: Tesar C]] | |
| - | [[Category: Sacchettini | + | |
| - | [[Category: Tesar | + | |
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Revision as of 06:47, 2 March 2023
Crystal Structure of New Delhi Metallo-beta-Lactamase-1 Mutant M67V Complexed with Hydrolyzed Penicillin G
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