4rcz

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==Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GDPNP==
==Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GDPNP==
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<StructureSection load='4rcz' size='340' side='right' caption='[[4rcz]], [[Resolution|resolution]] 1.43&Aring;' scene=''>
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<StructureSection load='4rcz' size='340' side='right'caption='[[4rcz]], [[Resolution|resolution]] 1.43&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rcz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RCZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RCZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rcz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus_P2 Saccharolobus solfataricus P2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RCZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RCZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rcy|4rcy]], [[4rd0|4rd0]], [[4rd1|4rd1]], [[4rd2|4rd2]], [[4rd3|4rd3]], [[4rd4|4rd4]], [[4rd6|4rd6]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rcz OCA], [https://pdbe.org/4rcz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rcz RCSB], [https://www.ebi.ac.uk/pdbsum/4rcz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rcz ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eif2g, SSO0412, sulfolobus solfataricus ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273057 SULSO])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rcz OCA], [http://pdbe.org/4rcz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rcz RCSB], [http://www.ebi.ac.uk/pdbsum/4rcz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rcz ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IF2G_SULSO IF2G_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).
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[https://www.uniprot.org/uniprot/IF2G_SACS2 IF2G_SACS2] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00119]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Sulso]]
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[[Category: Large Structures]]
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[[Category: Aleksandrov, A]]
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[[Category: Saccharolobus solfataricus P2]]
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[[Category: Dubiez, E]]
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[[Category: Aleksandrov A]]
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[[Category: Lazennec-Schurdevin, C]]
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[[Category: Dubiez E]]
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[[Category: Mechulam, Y]]
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[[Category: Lazennec-Schurdevin C]]
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[[Category: Schmitt, E]]
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[[Category: Mechulam Y]]
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[[Category: Rossmann fold]]
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[[Category: Schmitt E]]
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[[Category: Translation]]
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Revision as of 06:50, 2 March 2023

Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GDPNP

PDB ID 4rcz

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