8fwl
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Australian bat lyssavirus nucleoprotein in complex with phosphoprotein chaperone== | |
| - | + | <StructureSection load='8fwl' size='340' side='right'caption='[[8fwl]], [[Resolution|resolution]] 2.19Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8fwl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lyssavirus_australis Lyssavirus australis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FWL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fwl OCA], [https://pdbe.org/8fwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fwl RCSB], [https://www.ebi.ac.uk/pdbsum/8fwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fwl ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/Q9YZ24_9RHAB Q9YZ24_9RHAB] [https://www.uniprot.org/uniprot/A0A7M4C440_9RHAB A0A7M4C440_9RHAB] Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus.[RuleBase:RU004918] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lyssavirus australis]] | ||
| + | [[Category: Donnelly CM]] | ||
| + | [[Category: Forwood JK]] | ||
| + | [[Category: Stewart M]] | ||
Revision as of 07:37, 8 March 2023
Crystal structure of Australian bat lyssavirus nucleoprotein in complex with phosphoprotein chaperone
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