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2mlx

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==NMR structure of E. coli Trigger Factor in complex with unfolded PhoA220-310==
==NMR structure of E. coli Trigger Factor in complex with unfolded PhoA220-310==
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<StructureSection load='2mlx' size='340' side='right'caption='[[2mlx]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2mlx' size='340' side='right'caption='[[2mlx]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2mlx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._k-12_substr._mc4100 Escherichia coli str. k-12 substr. mc4100]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MLX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2mlx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._MC4100 Escherichia coli str. K-12 substr. MC4100]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MLX FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2mly|2mly]], [[2mlz|2mlz]]</div></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mlx OCA], [https://pdbe.org/2mlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mlx RCSB], [https://www.ebi.ac.uk/pdbsum/2mlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mlx ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tig, BN896_0318 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1403831 Escherichia coli str. K-12 substr. MC4100]), phoA, BN896_0267 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1403831 Escherichia coli str. K-12 substr. MC4100])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mlx OCA], [https://pdbe.org/2mlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mlx RCSB], [https://www.ebi.ac.uk/pdbsum/2mlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mlx ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
 
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[[https://www.uniprot.org/uniprot/U6N325_ECOLI U6N325_ECOLI]] Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation (By similarity).[RuleBase:RU003914] Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).[HAMAP-Rule:MF_00303]
 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli str. k-12 substr. mc4100]]
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[[Category: Escherichia coli str. K-12 substr. MC4100]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Economou A]]
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[[Category: Economou, A]]
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[[Category: Guan X]]
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[[Category: Guan, X]]
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[[Category: Kalodimos CG]]
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[[Category: Kalodimos, C G]]
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[[Category: Rossi P]]
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[[Category: Rossi, P]]
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[[Category: Saio T]]
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[[Category: Saio, T]]
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[[Category: Chaperone]]
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[[Category: Molecular chaperone]]
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[[Category: Protein complex]]
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[[Category: Unfolded protein]]
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Revision as of 08:01, 8 March 2023

NMR structure of E. coli Trigger Factor in complex with unfolded PhoA220-310

PDB ID 2mlx

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