2mq9

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==Solution structure of E55Q mutant of eRF1 N-domain==
==Solution structure of E55Q mutant of eRF1 N-domain==
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<StructureSection load='2mq9' size='340' side='right'caption='[[2mq9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2mq9' size='340' side='right'caption='[[2mq9]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2mq9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MQ9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2mq9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MQ9 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ERF1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mq9 OCA], [https://pdbe.org/2mq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mq9 RCSB], [https://www.ebi.ac.uk/pdbsum/2mq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mq9 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mq9 OCA], [https://pdbe.org/2mq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mq9 RCSB], [https://www.ebi.ac.uk/pdbsum/2mq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mq9 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ERF1_HUMAN ERF1_HUMAN]] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.<ref>PMID:7990965</ref>
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[https://www.uniprot.org/uniprot/ERF1_HUMAN ERF1_HUMAN] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.<ref>PMID:7990965</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Li, Y]]
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[[Category: Li Y]]
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[[Category: Pervushin, K]]
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[[Category: Pervushin K]]
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[[Category: Pillay, S]]
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[[Category: Pillay S]]
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[[Category: Wong, L]]
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[[Category: Wong L]]
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[[Category: Erf1]]
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[[Category: Rdc]]
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[[Category: Translation]]
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[[Category: Translation termination]]
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Revision as of 08:04, 8 March 2023

Solution structure of E55Q mutant of eRF1 N-domain

PDB ID 2mq9

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