2mqo

<StructureSection load='2mqo' size='340' side='right'caption='[[2mqo]]' scene=''>

<table><tr><td colspan='2'>[[2mqo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MQO FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mqo OCA], [https://pdbe.org/2mqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mqo RCSB], [https://www.ebi.ac.uk/pdbsum/2mqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mqo ProSAT]</span></td></tr>

== Function ==

[https://www.uniprot.org/uniprot/HNRPL_RAT HNRPL_RAT] Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter. As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPK and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation (By similarity).[UniProtKB:P14866]

[[Category: Rattus norvegicus]]

[[Category: Allain F]]

[[Category: Blatter M]]