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4rs3

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==Crystal structure of carbohydrate transporter A0QYB3 from Mycobacterium smegmatis str. MC2 155, target EFI-510969, in complex with xylitol==
==Crystal structure of carbohydrate transporter A0QYB3 from Mycobacterium smegmatis str. MC2 155, target EFI-510969, in complex with xylitol==
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<StructureSection load='4rs3' size='340' side='right' caption='[[4rs3]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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<StructureSection load='4rs3' size='340' side='right'caption='[[4rs3]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rs3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycs2 Mycs2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RS3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rs3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RS3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=XYL:D-XYLITOL'>XYL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=XYL:D-XYLITOL'>XYL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rs3 OCA], [https://pdbe.org/4rs3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rs3 RCSB], [https://www.ebi.ac.uk/pdbsum/4rs3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rs3 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MSMEG_3598, MSMEI_3515 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=246196 MYCS2])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Monosaccharide-transporting_ATPase Monosaccharide-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.17 3.6.3.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rs3 OCA], [http://pdbe.org/4rs3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rs3 RCSB], [http://www.ebi.ac.uk/pdbsum/4rs3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rs3 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/XYPA_MYCS2 XYPA_MYCS2] Part of an ABC transporter complex likely involved in xylitol import. Binds xylitol.<ref>PMID:26560079</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Monosaccharide-transporting ATPase]]
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[[Category: Large Structures]]
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[[Category: Mycs2]]
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[[Category: Mycolicibacterium smegmatis MC2 155]]
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[[Category: Almo, S C]]
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[[Category: Al Obaidi N]]
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[[Category: Attonito, J D]]
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[[Category: Almo SC]]
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[[Category: Bhosle, R]]
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[[Category: Attonito JD]]
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[[Category: Chamala, S]]
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[[Category: Bhosle R]]
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[[Category: Chowdhury, S]]
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[[Category: Chamala S]]
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[[Category: EFI, Enzyme Function Initiative]]
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[[Category: Chowdhury S]]
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[[Category: Gerlt, J A]]
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[[Category: Gerlt JA]]
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[[Category: Glenn, A Scott]]
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[[Category: Hillerich B]]
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[[Category: Hillerich, B]]
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[[Category: Lafleur J]]
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[[Category: Lafleur, J]]
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[[Category: Love J]]
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[[Category: Love, J]]
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[[Category: Morisco LL]]
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[[Category: Morisco, L L]]
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[[Category: Patskovsky Y]]
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[[Category: Obaidi, N Al]]
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[[Category: Scott Glenn A]]
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[[Category: Patskovsky, Y]]
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[[Category: Siedel RD]]
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[[Category: Siedel, R D]]
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[[Category: Toro R]]
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[[Category: Toro, R]]
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[[Category: Wasserman SR]]
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[[Category: Wasserman, S R]]
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[[Category: Whalen KL]]
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[[Category: Whalen, K L]]
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[[Category: Abc-type]]
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[[Category: Efi]]
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[[Category: Enzyme function initiative]]
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[[Category: Hydrolase]]
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[[Category: Structural genomic]]
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[[Category: Sugar transporter]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of carbohydrate transporter A0QYB3 from Mycobacterium smegmatis str. MC2 155, target EFI-510969, in complex with xylitol

PDB ID 4rs3

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