4s2q

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<StructureSection load='4s2q' size='340' side='right'caption='[[4s2q]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4s2q' size='340' side='right'caption='[[4s2q]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4s2q]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S2Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4S2Q FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4s2q]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4S2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4S2Q FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Sox9, Sox-9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4s2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s2q OCA], [https://pdbe.org/4s2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4s2q RCSB], [https://www.ebi.ac.uk/pdbsum/4s2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4s2q ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4s2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4s2q OCA], [http://pdbe.org/4s2q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4s2q RCSB], [http://www.ebi.ac.uk/pdbsum/4s2q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4s2q ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SOX9_MOUSE SOX9_MOUSE]] Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes (By similarity).
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[https://www.uniprot.org/uniprot/SOX9_MOUSE SOX9_MOUSE] Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Kolatkar, P R]]
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[[Category: Synthetic construct]]
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[[Category: Lescar, J]]
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[[Category: Kolatkar PR]]
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[[Category: Moovarkumudalvan, B]]
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[[Category: Lescar J]]
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[[Category: Vivekanandan, S]]
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[[Category: Moovarkumudalvan B]]
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[[Category: Dna bending]]
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[[Category: Vivekanandan S]]
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[[Category: Dna binding protein-dna complex]]
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[[Category: Minor groove binding]]
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[[Category: Transcription regulation]]
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Revision as of 10:40, 15 March 2023

Crystal Structure of HMG domain of the chondrogenesis master regulator, Sox9 in complex with ChIP-Seq identified DNA element

PDB ID 4s2q

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