7z2l

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'''Unreleased structure'''
 
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The entry 7z2l is ON HOLD until Paper Publication
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==Crystal structure of L-Kynurenine in the active site of human Indoleamine-2,3-dioxygenase 1 (hIDO1)==
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<StructureSection load='7z2l' size='340' side='right'caption='[[7z2l]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
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Authors: Mirgaux, M., Wouters, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7z2l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z2L FirstGlance]. <br>
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Description: Crystal structure of L-Kynurenine in the active site of human Indoleamine-2,3-dioxygenase 1 (hIDO1)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=KYN:(2S)-2-AMINO-4-(2-AMINOPHENYL)-4-OXOBUTANOIC+ACID'>KYN</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z2l OCA], [https://pdbe.org/7z2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z2l RCSB], [https://www.ebi.ac.uk/pdbsum/7z2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z2l ProSAT]</span></td></tr>
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[[Category: Wouters, J]]
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</table>
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[[Category: Mirgaux, M]]
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== Function ==
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[https://www.uniprot.org/uniprot/I23O1_HUMAN I23O1_HUMAN] Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.<ref>PMID:17671174</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Mirgaux M]]
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[[Category: Wouters J]]

Revision as of 07:17, 22 March 2023

Crystal structure of L-Kynurenine in the active site of human Indoleamine-2,3-dioxygenase 1 (hIDO1)

PDB ID 7z2l

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