8ar2
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of TLR5 transmembrane and cytoplasmic juxtamembrane regions== | |
| - | + | <StructureSection load='8ar2' size='340' side='right'caption='[[8ar2]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ar2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AR2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ar2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ar2 OCA], [https://pdbe.org/8ar2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ar2 RCSB], [https://www.ebi.ac.uk/pdbsum/8ar2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ar2 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/TLR5_HUMAN TLR5_HUMAN] Disease susceptibility is associated with variations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TLR5_HUMAN TLR5_HUMAN] Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.<ref>PMID:11323673</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arseniev AS]] | ||
| + | [[Category: Goncharuk MV]] | ||
| + | [[Category: Goncharuk SA]] | ||
| + | [[Category: Kornilov FD]] | ||
| + | [[Category: Mineev KS]] | ||
| + | [[Category: Shabalkina AV]] | ||
Revision as of 07:20, 22 March 2023
Solution structure of TLR5 transmembrane and cytoplasmic juxtamembrane regions
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