8g8e

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m (Protected "8g8e" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 8g8e is ON HOLD
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==Human Oct4 bound to nucleosome with human LIN28B sequence==
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<StructureSection load='8g8e' size='340' side='right'caption='[[8g8e]], [[Resolution|resolution]] 4.20&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8g8e]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8G8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8G8E FirstGlance]. <br>
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Description:
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8g8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8g8e OCA], [https://pdbe.org/8g8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8g8e RCSB], [https://www.ebi.ac.uk/pdbsum/8g8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8g8e ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PO5F1_HUMAN PO5F1_HUMAN] Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.<ref>PMID:18035408</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Bilokapic S]]
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[[Category: Du Y]]
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[[Category: Halic M]]
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[[Category: Malik D]]
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[[Category: Sinha KK]]

Revision as of 07:27, 22 March 2023

Human Oct4 bound to nucleosome with human LIN28B sequence

PDB ID 8g8e

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OCA

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