8gyw
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Structural basis for catalysis of human choline/ethanolamine phosphotransferase (CEPT1) complexed with CDP-choline== | |
- | + | <StructureSection load='8gyw' size='340' side='right'caption='[[8gyw]], [[Resolution|resolution]] 3.90Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[8gyw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GYW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GYW FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDC:[2-CYTIDYLATE-O-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM'>CDC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gyw OCA], [https://pdbe.org/8gyw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gyw RCSB], [https://www.ebi.ac.uk/pdbsum/8gyw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gyw ProSAT]</span></td></tr> |
- | [[Category: | + | </table> |
- | [[Category: Qian | + | == Function == |
+ | [https://www.uniprot.org/uniprot/CEPT1_HUMAN CEPT1_HUMAN] Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity.<ref>PMID:10191259</ref> <ref>PMID:10893425</ref> <ref>PMID:12216837</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Qian HW]] | ||
+ | [[Category: Wang ZH]] |
Revision as of 07:28, 22 March 2023
Structural basis for catalysis of human choline/ethanolamine phosphotransferase (CEPT1) complexed with CDP-choline
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