8gyx
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structural basis for catalysis of human choline/ethanolamine phosphotransferase (CEPT1)== | |
| - | + | <StructureSection load='8gyx' size='340' side='right'caption='[[8gyx]], [[Resolution|resolution]] 3.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8gyx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GYX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gyx OCA], [https://pdbe.org/8gyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gyx RCSB], [https://www.ebi.ac.uk/pdbsum/8gyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gyx ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Qian | + | == Function == |
| + | [https://www.uniprot.org/uniprot/CEPT1_HUMAN CEPT1_HUMAN] Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity.<ref>PMID:10191259</ref> <ref>PMID:10893425</ref> <ref>PMID:12216837</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Qian HW]] | ||
| + | [[Category: Wang ZH]] | ||
Revision as of 07:28, 22 March 2023
Structural basis for catalysis of human choline/ethanolamine phosphotransferase (CEPT1)
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