4uvh

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<StructureSection load='4uvh' size='340' side='right'caption='[[4uvh]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
<StructureSection load='4uvh' size='340' side='right'caption='[[4uvh]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4uvh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UVH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4uvh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UVH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=UUD:N-(1,3-BENZOTHIAZOL-2-YL)ACETAMIDE'>UUD</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=UUD:N-(1,3-BENZOTHIAZOL-2-YL)ACETAMIDE'>UUD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uvd|4uvd]], [[4uve|4uve]], [[4uvg|4uvg]], [[4uvi|4uvi]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uvh OCA], [https://pdbe.org/4uvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uvh RCSB], [https://www.ebi.ac.uk/pdbsum/4uvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uvh ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uvh OCA], [http://pdbe.org/4uvh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uvh RCSB], [http://www.ebi.ac.uk/pdbsum/4uvh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uvh ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU]
==See Also==
==See Also==
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*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]
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*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Cowan, S]]
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[[Category: Cowan S]]
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[[Category: Ghorpade, S]]
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[[Category: Ghorpade S]]
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[[Category: Gingell, H]]
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[[Category: Gingell H]]
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[[Category: Madhavapeddi, P]]
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[[Category: Madhavapeddi P]]
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[[Category: Read, J A]]
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[[Category: Read JA]]
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[[Category: Acp enoyl reductase]]
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[[Category: Fblg]]
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[[Category: Inha]]
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[[Category: Oxidoreductase]]
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[[Category: Pyrimidine isoxazole]]
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Revision as of 07:42, 29 March 2023

Discovery of pyrimidine isoxazoles InhA in complex with compound 10

PDB ID 4uvh

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