4v06
From Proteopedia
(Difference between revisions)
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<StructureSection load='4v06' size='340' side='right'caption='[[4v06]], [[Resolution|resolution]] 2.63Å' scene=''> | <StructureSection load='4v06' size='340' side='right'caption='[[4v06]], [[Resolution|resolution]] 2.63Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4v06]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4v06]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V06 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v06 OCA], [https://pdbe.org/4v06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v06 RCSB], [https://www.ebi.ac.uk/pdbsum/4v06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v06 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TPH2_HUMAN TPH2_HUMAN] Disease susceptibility is associated with variations affecting the gene represented in this entry. Disease susceptibility is associated with variations affecting the gene represented in this entry. Naturally occurring variants of TPH2 with impaired enzyme activity could cause deficiency of serotonin production and result in an increased risk of developing behavioral disorders. |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TPH2_HUMAN TPH2_HUMAN] | ||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Arrowsmith C]] | |
| - | [[Category: Arrowsmith | + | [[Category: Bountra C]] |
| - | [[Category: Bountra | + | [[Category: Burgess-Brown N]] |
| - | [[Category: Burgess-Brown | + | [[Category: Edwards A]] |
| - | + | [[Category: Fitzpatrick F]] | |
| - | [[Category: Edwards | + | [[Category: Kiyani W]] |
| - | [[Category: Fitzpatrick | + | [[Category: Kopec J]] |
| - | [[Category: Kiyani | + | [[Category: Newman J]] |
| - | [[Category: Kopec | + | [[Category: Oberholzer A]] |
| - | [[Category: Newman | + | [[Category: Shrestha L]] |
| - | [[Category: Oberholzer | + | [[Category: Tallant C]] |
| - | [[Category: Shrestha | + | [[Category: Yue WW]] |
| - | [[Category: Tallant | + | [[Category: Von Delft F]] |
| - | [[Category: Yue | + | |
| - | [[Category: | + | |
Revision as of 07:55, 29 March 2023
Crystal structure of human tryptophan hydroxylase 2 (TPH2), catalytic domain
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Bountra C | Burgess-Brown N | Edwards A | Fitzpatrick F | Kiyani W | Kopec J | Newman J | Oberholzer A | Shrestha L | Tallant C | Yue WW | Von Delft F
