1kd3
From Proteopedia
| Line 1: | Line 1: | ||
[[Image:1kd3.gif|left|200px]] | [[Image:1kd3.gif|left|200px]] | ||
| - | + | <!-- | |
| - | + | The line below this paragraph, containing "STRUCTURE_1kd3", creates the "Structure Box" on the page. | |
| - | + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | |
| - | + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |
| - | | | + | or leave the SCENE parameter empty for the default display. |
| - | | | + | --> |
| - | + | {{STRUCTURE_1kd3| PDB=1kd3 | SCENE= }} | |
| - | + | ||
| - | + | ||
| - | }} | + | |
'''The Crystal Structure of r(GGUCACAGCCC)2, Thallium form''' | '''The Crystal Structure of r(GGUCACAGCCC)2, Thallium form''' | ||
| Line 19: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | + | Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KD3 OCA]. | |
==Reference== | ==Reference== | ||
Crystal structures of r(GGUCACAGCCC)2., Kacer V, Scaringe SA, Scarsdale JN, Rife JP, Acta Crystallogr D Biol Crystallogr. 2003 Mar;59(Pt 3):423-32. Epub 2003, Feb 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12595698 12595698] | Crystal structures of r(GGUCACAGCCC)2., Kacer V, Scaringe SA, Scarsdale JN, Rife JP, Acta Crystallogr D Biol Crystallogr. 2003 Mar;59(Pt 3):423-32. Epub 2003, Feb 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12595698 12595698] | ||
| - | [[Category: Protein complex]] | ||
[[Category: Kacer, V.]] | [[Category: Kacer, V.]] | ||
[[Category: Rife, J P.]] | [[Category: Rife, J P.]] | ||
[[Category: Scaringe, S A.]] | [[Category: Scaringe, S A.]] | ||
[[Category: Scarsdale, J N.]] | [[Category: Scarsdale, J N.]] | ||
| - | [[Category: | + | [[Category: Metal binding]] |
| - | [[Category: | + | [[Category: Rna duplex]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:35:41 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 19:35, 2 May 2008
The Crystal Structure of r(GGUCACAGCCC)2, Thallium form
Overview
Crystals of small RNAs, which regularly diffract to very high resolution, can often be readily obtained. Unfortunately, for some RNAs the conformations adopted in the crystalline form are different from those found in solution. For example, short RNAs that form hairpins in solution virtually never crystallize thus; rather, they form duplexes. Nevertheless, these unintended structures have contributed greatly to the understanding of RNA structure. In a similar occurrence, the homodimer r(GGUCACAGCCC)(2) has been crystallized from an 11-mer/12-mer heteroduplex, r(GGCUGAAGUCCG)/r(GGUCACAGCCC). This surprising phenomenon was observed under a variety of crystallization conditions. The structure of the homoduplex was determined from crystals that differed in the precipitant used and the type of metal present. In all cases, the resulting homoduplexes contain ten base pairings, of which the central six are non-canonical pairings. In two of the variants, ordered metal-binding sites were observed: two equivalent octacoordinate Tl(+) sites in one and two equivalent nanocoordinate Ba(2+) sites in another.
About this Structure
Full crystallographic information is available from OCA.
Reference
Crystal structures of r(GGUCACAGCCC)2., Kacer V, Scaringe SA, Scarsdale JN, Rife JP, Acta Crystallogr D Biol Crystallogr. 2003 Mar;59(Pt 3):423-32. Epub 2003, Feb 21. PMID:12595698 Page seeded by OCA on Fri May 2 22:35:41 2008
