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4v2g
From Proteopedia
(Difference between revisions)
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<StructureSection load='4v2g' size='340' side='right'caption='[[4v2g]], [[Resolution|resolution]] 2.71Å' scene=''> | <StructureSection load='4v2g' size='340' side='right'caption='[[4v2g]], [[Resolution|resolution]] 2.71Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4v2g]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4v2g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1bjy 1bjy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V2G FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CTC:7-CHLOROTETRACYCLINE'>CTC</scene>, <scene name='pdbligand=ITC:ISO-7-CHLORTETRACYCLINE'>ITC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTC:7-CHLOROTETRACYCLINE'>CTC</scene>, <scene name='pdbligand=ITC:ISO-7-CHLORTETRACYCLINE'>ITC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v2g OCA], [https://pdbe.org/4v2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v2g RCSB], [https://www.ebi.ac.uk/pdbsum/4v2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v2g ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TETR4_ECOLX TETR4_ECOLX] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Tetracycline repressor protein|Tetracycline repressor protein]] | + | *[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Hinrichs | + | [[Category: Hinrichs W]] |
| - | [[Category: Orth | + | [[Category: Orth P]] |
| - | [[Category: Saenger | + | [[Category: Saenger W]] |
| - | [[Category: Werten | + | [[Category: Werten S]] |
| - | + | ||
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Revision as of 07:59, 29 March 2023
Tetracycline repressor TetR(D) bound to chlortetracycline and iso- chlortetracycline
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