4v60

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<StructureSection load='4v60' size='340' side='right'caption='[[4v60]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
<StructureSection load='4v60' size='340' side='right'caption='[[4v60]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4v60]] is a 39 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zuo 2zuo], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zv4 2zv4] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zv5 2zv5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V60 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4v60]] is a 39 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zuo 2zuo], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zv4 2zv4] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zv5 2zv5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V60 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v60 OCA], [http://pdbe.org/4v60 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4v60 RCSB], [http://www.ebi.ac.uk/pdbsum/4v60 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4v60 ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v60 OCA], [https://pdbe.org/4v60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v60 RCSB], [https://www.ebi.ac.uk/pdbsum/4v60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v60 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MVP_RAT MVP_RAT]] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity).
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[https://www.uniprot.org/uniprot/MVP_RAT MVP_RAT] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4v60" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4v60" style="background-color:#fffaf0;"></div>
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==See Also==
 
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*[[Major vault protein|Major vault protein]]
 
== References ==
== References ==
<references/>
<references/>
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Kato, K]]
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[[Category: Kato K]]
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[[Category: Tanaka, H]]
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[[Category: Tanaka H]]
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[[Category: Tsukihara, T]]
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[[Category: Tsukihara T]]
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[[Category: Yamashita, E]]
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[[Category: Yamashita E]]
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[[Category: Yao, M]]
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[[Category: Yao M]]
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[[Category: Yoshimura, M]]
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[[Category: Yoshimura M]]
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[[Category: Zhou, Y]]
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[[Category: Zhou Y]]
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[[Category: Repeat domain]]
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[[Category: Protein-protein complex]]
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[[Category: Ribonucleoprotein]]
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[[Category: Structural protein]]
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Revision as of 08:06, 29 March 2023

The structure of rat liver vault at 3.5 angstrom resolution

PDB ID 4v60

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Proteopedia Page Contributors and Editors (what is this?)

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