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4wlz

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==Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese and UDP==
==Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese and UDP==
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<StructureSection load='4wlz' size='340' side='right' caption='[[4wlz]], [[Resolution|resolution]] 3.03&Aring;' scene=''>
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<StructureSection load='4wlz' size='340' side='right'caption='[[4wlz]], [[Resolution|resolution]] 3.03&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4wlz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WLZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WLZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4wlz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WLZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WLZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wlg|4wlg]], [[4wlm|4wlm]], [[4wm0|4wm0]], [[4wma|4wma]], [[4wmb|4wmb]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wlz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wlz OCA], [https://pdbe.org/4wlz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wlz RCSB], [https://www.ebi.ac.uk/pdbsum/4wlz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wlz ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Xxylt1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wlz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wlz OCA], [http://pdbe.org/4wlz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wlz RCSB], [http://www.ebi.ac.uk/pdbsum/4wlz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wlz ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/XXLT1_MOUSE XXLT1_MOUSE]] Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of the second xylose.
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[https://www.uniprot.org/uniprot/XXLT1_MOUSE XXLT1_MOUSE] Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of the second xylose.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Li, H]]
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[[Category: Mus musculus]]
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[[Category: Yu, H]]
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[[Category: Li H]]
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[[Category: Glycosyltransferase]]
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[[Category: Yu H]]
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[[Category: Transferase]]
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Revision as of 07:15, 7 April 2023

Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese and UDP

PDB ID 4wlz

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