8gva

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (20:34, 12 April 2023) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8gva is ON HOLD until Paper Publication
+
==The intermediate structure of hAE2 in basic pH==
-
 
+
<StructureSection load='8gva' size='340' side='right'caption='[[8gva]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
-
Authors: Zhang, Q., Jian, L., Yao, D., Rao, B., Hu, K., Xia, Y., Cao, Y.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8gva]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GVA FirstGlance]. <br>
-
Description: The intermediate structure of hAE2 in basic pH
+
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gva OCA], [https://pdbe.org/8gva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gva RCSB], [https://www.ebi.ac.uk/pdbsum/8gva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gva ProSAT]</span></td></tr>
-
[[Category: Unreleased Structures]]
+
</table>
-
[[Category: Cao, Y]]
+
== Function ==
-
[[Category: Rao, B]]
+
[https://www.uniprot.org/uniprot/B3A2_HUMAN B3A2_HUMAN] Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane (PubMed:15184086, PubMed:34668226). Plays an important role in osteoclast differentiation and function (PubMed:34668226). Regulates bone resorption and calpain-dependent actin cytoskeleton organization in osteoclasts via anion exchange-dependent control of pH (By similarity). Essential for intracellular pH regulation in CD8(+) T-cells upon CD3 stimulation, modulating CD8(+) T-cell responses (By similarity).[UniProtKB:P13808]<ref>PMID:15184086</ref> <ref>PMID:34668226</ref>
-
[[Category: Hu, K]]
+
== References ==
-
[[Category: Jian, L]]
+
<references/>
-
[[Category: Yao, D]]
+
__TOC__
-
[[Category: Xia, Y]]
+
</StructureSection>
-
[[Category: Zhang, Q]]
+
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Cao Y]]
 +
[[Category: Hu K]]
 +
[[Category: Jian L]]
 +
[[Category: Rao B]]
 +
[[Category: Xia Y]]
 +
[[Category: Yao D]]
 +
[[Category: Zhang Q]]

Current revision

The intermediate structure of hAE2 in basic pH

PDB ID 8gva

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8gva"
Personal tools