4x46

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<StructureSection load='4x46' size='340' side='right'caption='[[4x46]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4x46' size='340' side='right'caption='[[4x46]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4x46]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X46 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X46 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4x46]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X46 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X46 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">deoA, STM4568 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x46 OCA], [https://pdbe.org/4x46 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x46 RCSB], [https://www.ebi.ac.uk/pdbsum/4x46 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x46 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidine_phosphorylase Thymidine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.4 2.4.2.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x46 OCA], [http://pdbe.org/4x46 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x46 RCSB], [http://www.ebi.ac.uk/pdbsum/4x46 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x46 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TYPH_SALTY TYPH_SALTY]] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
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[https://www.uniprot.org/uniprot/TYPH_SALTY TYPH_SALTY] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus typhimurium loeffler 1892]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thymidine phosphorylase]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Balaev, V V]]
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[[Category: Balaev VV]]
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[[Category: Betzel, C]]
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[[Category: Betzel C]]
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[[Category: Gabdoulkhakov, A G]]
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[[Category: Gabdoulkhakov AG]]
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[[Category: Lashkov, A A]]
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[[Category: Lashkov AA]]
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[[Category: Mikhailov, A M]]
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[[Category: Mikhailov AM]]
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[[Category: Prokofev, I I]]
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[[Category: Prokofev II]]
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[[Category: Metabolism]]
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[[Category: Nucleoside]]
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[[Category: Transferase]]
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Revision as of 21:11, 12 April 2023

X-RAY structure thymidine phosphorylase from Salmonella typhimurium complex with SO4 at 2.19 A

PDB ID 4x46

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