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4x51

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<StructureSection load='4x51' size='340' side='right'caption='[[4x51]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='4x51' size='340' side='right'caption='[[4x51]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4x51]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X51 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X51 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4x51]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X51 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X51 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Il10, Il-10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x51 OCA], [https://pdbe.org/4x51 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x51 RCSB], [https://www.ebi.ac.uk/pdbsum/4x51 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x51 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x51 OCA], [http://pdbe.org/4x51 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x51 RCSB], [http://www.ebi.ac.uk/pdbsum/4x51 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x51 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IL10_MOUSE IL10_MOUSE]] Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
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[https://www.uniprot.org/uniprot/IL10_MOUSE IL10_MOUSE] Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
==See Also==
==See Also==
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*[[Interleukin|Interleukin]]
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*[[Interleukin 3D structures|Interleukin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Kuenze, G]]
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[[Category: Kuenze G]]
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[[Category: Cytokine]]
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[[Category: Helix bundle]]
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[[Category: Immune system]]
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[[Category: Interleukin-10 family]]
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Revision as of 21:12, 12 April 2023

X-ray structure of mouse interleukin-10 mutant - S1_E8del, C149Y

PDB ID 4x51

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