4x9j
From Proteopedia
(Difference between revisions)
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==EGR-1 with Doubly Methylated DNA== | ==EGR-1 with Doubly Methylated DNA== | ||
| - | <StructureSection load='4x9j' size='340' side='right' caption='[[4x9j]], [[Resolution|resolution]] 1.41Å' scene=''> | + | <StructureSection load='4x9j' size='340' side='right'caption='[[4x9j]], [[Resolution|resolution]] 1.41Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4x9j]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4x9j]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X9J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X9J FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x9j OCA], [https://pdbe.org/4x9j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x9j RCSB], [https://www.ebi.ac.uk/pdbsum/4x9j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x9j ProSAT]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/EGR1_HUMAN EGR1_HUMAN] Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Synthetic construct]] |
| - | [[Category: | + | [[Category: Iwahara J]] |
| - | [[Category: | + | [[Category: White MA]] |
| - | [[Category: | + | [[Category: Zandarashvili L]] |
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Revision as of 21:19, 12 April 2023
EGR-1 with Doubly Methylated DNA
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