7zho

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'''Unreleased structure'''
 
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The entry 7zho is ON HOLD until Paper Publication
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==Crystal structure of TTBK1 in complex with compound 3 (7-001)==
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<StructureSection load='7zho' size='340' side='right'caption='[[7zho]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
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Authors: Chaikuad, A., Axtman, A., Knapp, S., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7zho]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZHO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZHO FirstGlance]. <br>
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Description: Crystal structure of TTBK1 in complex with compound 3 (7-001)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IQR:4-[3-(2-azanylpyrimidin-4-yl)-1~{H}-indol-5-yl]-2-methyl-but-3-yn-2-ol'>IQR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zho FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zho OCA], [https://pdbe.org/7zho PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zho RCSB], [https://www.ebi.ac.uk/pdbsum/7zho PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zho ProSAT]</span></td></tr>
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[[Category: Chaikuad, A]]
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</table>
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[[Category: Axtman, A]]
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== Function ==
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[[Category: Knapp, S]]
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[https://www.uniprot.org/uniprot/TTBK1_HUMAN TTBK1_HUMAN] Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.<ref>PMID:16923168</ref>
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[[Category: Structural Genomics Consortium (Sgc)]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Axtman A]]
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[[Category: Chaikuad A]]
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[[Category: Knapp S]]

Revision as of 09:23, 19 April 2023

Crystal structure of TTBK1 in complex with compound 3 (7-001)

PDB ID 7zho

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