7zgo

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'''Unreleased structure'''
 
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The entry 7zgo is ON HOLD until Paper Publication
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==Cryo-EM structure of human NKCC1 (TM domain)==
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<StructureSection load='7zgo' size='340' side='right'caption='[[7zgo]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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Authors: Nissen, P., Fenton, R., Neumann, C., Lindtoft Rosenbaek, L., Kock Flygaard, R., Habeck, M., Lykkegaard Karlsen, J., Wang, Y., Lindorff-Larsen, K., Gad, H., Hartmann, R., Lyons, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7zgo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZGO FirstGlance]. <br>
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Description: Cryo-EM structure of human NKCC1 (TM domain)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zgo OCA], [https://pdbe.org/7zgo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zgo RCSB], [https://www.ebi.ac.uk/pdbsum/7zgo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zgo ProSAT]</span></td></tr>
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[[Category: Hartmann, R]]
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</table>
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[[Category: Lykkegaard Karlsen, J]]
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== Function ==
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[[Category: Habeck, M]]
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[https://www.uniprot.org/uniprot/S12A2_HUMAN S12A2_HUMAN] Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
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[[Category: Kock Flygaard, R]]
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__TOC__
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[[Category: Lindtoft Rosenbaek, L]]
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</StructureSection>
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[[Category: Lindorff-Larsen, K]]
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[[Category: Homo sapiens]]
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[[Category: Nissen, P]]
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[[Category: Large Structures]]
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[[Category: Lyons, J]]
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[[Category: Fenton R]]
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[[Category: Neumann, C]]
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[[Category: Gad H]]
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[[Category: Wang, Y]]
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[[Category: Habeck M]]
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[[Category: Fenton, R]]
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[[Category: Hartmann R]]
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[[Category: Gad, H]]
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[[Category: Kock Flygaard R]]
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[[Category: Lindorff-Larsen K]]
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[[Category: Lindtoft Rosenbaek L]]
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[[Category: Lykkegaard Karlsen J]]
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[[Category: Lyons J]]
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[[Category: Neumann C]]
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[[Category: Nissen P]]
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[[Category: Wang Y]]

Revision as of 09:41, 19 April 2023

Cryo-EM structure of human NKCC1 (TM domain)

PDB ID 7zgo

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