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Budesonide
From Proteopedia
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<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='96/962959/Cv/1'> | <StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='96/962959/Cv/1'> | ||
Budesonide, sold under the brand name Pulmicort among others, is a medication of the corticosteroid type. It is available as an inhaler, nebulization solution, pill, nasal spray, and rectal forms. The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease (COPD). The nasal spray is used for allergic rhinitis and nasal polyps. The pills in a delayed release form and rectal forms may be used for inflammatory bowel disease including Crohn's disease, ulcerative colitis, and microscopic colitis. See also [https://en.wikipedia.org/wiki/Budesonide]. | Budesonide, sold under the brand name Pulmicort among others, is a medication of the corticosteroid type. It is available as an inhaler, nebulization solution, pill, nasal spray, and rectal forms. The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease (COPD). The nasal spray is used for allergic rhinitis and nasal polyps. The pills in a delayed release form and rectal forms may be used for inflammatory bowel disease including Crohn's disease, ulcerative colitis, and microscopic colitis. See also [https://en.wikipedia.org/wiki/Budesonide]. | ||
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| + | Budesonide is an agonist of glucocorticoid receptors. Among its effects are: | ||
| + | *Controls the rate of protein synthesis. | ||
| + | *Depresses the migration of polymorphonuclear leukocytes and fibroblasts. | ||
| + | *Reverses capillary permeability and lysosomal stabilization at the cellular level to prevent or control inflammation. | ||
| + | *Has a potent glucocorticoid activity and weak mineralocorticoid activity. | ||
<scene name='96/962959/Tert/1'>Glucocorticoid Receptor in complex with budesonide</scene> ([[5nfp]]). | <scene name='96/962959/Tert/1'>Glucocorticoid Receptor in complex with budesonide</scene> ([[5nfp]]). | ||
Revision as of 11:53, 25 April 2023
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