7zka

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'''Unreleased structure'''
 
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The entry 7zka is ON HOLD until 2024-04-12
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==ABCB1 V978C mutant (mABCB1) in the outward facing state bound to AAC==
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<StructureSection load='7zka' size='340' side='right'caption='[[7zka]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7zka]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZKA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZKA FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=JIZ:(4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione'>JIZ</scene>, <scene name='pdbligand=LMN:LAURYL+MALTOSE+NEOPENTYL+GLYCOL'>LMN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zka OCA], [https://pdbe.org/7zka PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zka RCSB], [https://www.ebi.ac.uk/pdbsum/7zka PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zka ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Gewering T]]
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[[Category: Januliene D]]
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[[Category: Moeller A]]
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[[Category: Parey K]]
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[[Category: Urbatsch I]]
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[[Category: Zhang Q]]

Revision as of 17:01, 26 April 2023

ABCB1 V978C mutant (mABCB1) in the outward facing state bound to AAC

PDB ID 7zka

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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