4xju

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='4xju' size='340' side='right'caption='[[4xju]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
<StructureSection load='4xju' size='340' side='right'caption='[[4xju]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4xju]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJU FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4xju]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XJU FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=19D:(1R,2R,3R,4R,5R,7R)-2-(ACETYLAMINO)-7-[(1R)-1,2-DIHYDROXYETHYL]-4-FLUORO-3-HYDROXY-6,8-DIOXABICYCLO[3.2.1]OCTANE-5-CARBOXYLIC+ACID'>19D</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=19D:(1R,2R,3R,4R,5R,7R)-2-(ACETYLAMINO)-7-[(1R)-1,2-DIHYDROXYETHYL]-4-FLUORO-3-HYDROXY-6,8-DIOXABICYCLO[3.2.1]OCTANE-5-CARBOXYLIC+ACID'>19D</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nanB, SP_1687 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=170187 STRPN])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xju OCA], [https://pdbe.org/4xju PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xju RCSB], [https://www.ebi.ac.uk/pdbsum/4xju PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xju ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xju OCA], [http://pdbe.org/4xju PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xju RCSB], [http://www.ebi.ac.uk/pdbsum/4xju PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xju ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/NANB_STRPN NANB_STRPN]
==See Also==
==See Also==
-
*[[Sialidase|Sialidase]]
+
*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Exo-alpha-sialidase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Strpn]]
+
[[Category: Streptococcus pneumoniae TIGR4]]
-
[[Category: Brear, P]]
+
[[Category: Brear P]]
-
[[Category: Allosteric inhibitor]]
+
-
[[Category: Crystallization artefact]]
+
-
[[Category: Drug design]]
+
-
[[Category: Glycosidase]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Intramolecular trans-sialidase]]
+
-
[[Category: Neuraminidase]]
+
-
[[Category: Serendipitous allosteric site]]
+

Revision as of 17:40, 26 April 2023

Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 4-acetamido-2-fluoro-3-hydroxy-6-[1,2-dihydroxyethyl]-7,8-dioxabicyclo[3.2.1]octane-1-carboxylic acid

PDB ID 4xju

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools