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4xub

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<StructureSection load='4xub' size='340' side='right'caption='[[4xub]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
<StructureSection load='4xub' size='340' side='right'caption='[[4xub]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4xub]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XUB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4xub]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XUB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=43D:4-{4-(1-METHYL-1H-PYRAZOL-4-YL)-1-[2-(4-METHYL-1H-1,2,3-TRIAZOL-1-YL)ETHYL]-1H-IMIDAZOL-5-YL}BENZONITRILE'>43D</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=43D:4-{4-(1-METHYL-1H-PYRAZOL-4-YL)-1-[2-(4-METHYL-1H-1,2,3-TRIAZOL-1-YL)ETHYL]-1H-IMIDAZOL-5-YL}BENZONITRILE'>43D</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xua|4xua]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xub OCA], [https://pdbe.org/4xub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xub RCSB], [https://www.ebi.ac.uk/pdbsum/4xub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xub ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAZ2B, KIAA1476 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xub OCA], [http://pdbe.org/4xub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xub RCSB], [http://www.ebi.ac.uk/pdbsum/4xub PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xub ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.
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[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Chaikuad, A]]
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[[Category: Chaikuad A]]
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[[Category: Delft, F von]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M]]
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[[Category: Felletar I]]
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[[Category: Felletar, I]]
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[[Category: Knapp S]]
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[[Category: Knapp, S]]
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[[Category: Von Delft F]]
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[[Category: Structural genomic]]
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[[Category: Acetylated lysine binding protein]]
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[[Category: Bromodomain]]
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[[Category: Kiaa1476]]
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[[Category: Sgc]]
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[[Category: Transcription]]
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[[Category: Walp4]]
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Revision as of 17:52, 26 April 2023

Crystal Structure of the bromodomain of human BAZ2B in complex with BAZ2-ICR chemical probe

PDB ID 4xub

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