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4xze

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<StructureSection load='4xze' size='340' side='right'caption='[[4xze]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='4xze' size='340' side='right'caption='[[4xze]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4xze]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hazara_virus Hazara virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XZE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XZE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4xze]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hazara_virus Hazara virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XZE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XZE FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xz8|4xz8]], [[4xza|4xza]], [[4xzc|4xzc]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xze OCA], [https://pdbe.org/4xze PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xze RCSB], [https://www.ebi.ac.uk/pdbsum/4xze PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xze ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xze OCA], [http://pdbe.org/4xze PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xze RCSB], [http://www.ebi.ac.uk/pdbsum/4xze PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xze ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NCAP_HAZVJ NCAP_HAZVJ] Binds dsRNA and ssRNA and probably participates in the packaging of viral genome (By similarity). In the dsRNA binding mode, the nucleocapsid protein specifically binds to the vRNA panhandle secondary structure formed at the termini of viral genome (By similarity). Does not discriminate between viral and nonviral RNAs through ssRNA binding mode (By similarity). Displays dsDNA endonuclease activity that is sequence non-specific (By similarity).[UniProtKB:P89522]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Hazara virus]]
[[Category: Hazara virus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Guo, Y]]
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[[Category: Guo Y]]
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[[Category: Huo, T]]
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[[Category: Huo T]]
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[[Category: Liu, B]]
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[[Category: Liu B]]
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[[Category: Liu, X]]
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[[Category: Liu X]]
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[[Category: Wang, J]]
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[[Category: Wang J]]
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[[Category: Wang, W]]
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[[Category: Wang W]]
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[[Category: Wang, X]]
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[[Category: Wang X]]
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[[Category: Nucleoprotein]]
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[[Category: Rna binding protein]]
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Revision as of 17:59, 26 April 2023

The crystal structure of Hazara virus nucleoprotein

PDB ID 4xze

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OCA

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