4y0i

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<StructureSection load='4y0i' size='340' side='right'caption='[[4y0i]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
<StructureSection load='4y0i' size='340' side='right'caption='[[4y0i]], [[Resolution|resolution]] 1.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4y0i]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y0I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4y0i]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y0I FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PSZ:4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC+ACID'>PSZ</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PSZ:4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC+ACID'>PSZ</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ABAT, GABAT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y0i OCA], [https://pdbe.org/4y0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y0i RCSB], [https://www.ebi.ac.uk/pdbsum/4y0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y0i ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y0i OCA], [http://pdbe.org/4y0i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y0i RCSB], [http://www.ebi.ac.uk/pdbsum/4y0i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y0i ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GABT_PIG GABT_PIG]] Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
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[https://www.uniprot.org/uniprot/GABT_PIG GABT_PIG] Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pig]]
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[[Category: Sus scrofa]]
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[[Category: Dustin, D H]]
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[[Category: Dustin DH]]
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[[Category: Emma, D]]
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[[Category: Emma D]]
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[[Category: Lee, H V]]
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[[Category: Lee HV]]
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[[Category: Liu, D]]
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[[Category: Liu D]]
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[[Category: Neil, K]]
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[[Category: Neil K]]
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[[Category: Sanishvili, R]]
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[[Category: Sanishvili R]]
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[[Category: Silverman, R B]]
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[[Category: Silverman RB]]
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[[Category: Wu, R]]
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[[Category: Wu R]]
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[[Category: Biological evaluation]]
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[[Category: Mechanistic studies of con-formationally-restricted gaba-aminotransferase inactivator]]
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[[Category: Synthesis]]
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[[Category: Transferase]]
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Revision as of 18:01, 26 April 2023

GABA-aminotransferase inactivated by conformationally-restricted inactivator

PDB ID 4y0i

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