Sandbox Reserved 1799

From Proteopedia

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== Function of your protein ==
== Function of your protein ==
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Pyrrolysyl-tRNA synthase (PylRS) is a protein found in anaerobic archaea and bacteria. PylRS facilitates the installation of pyrrolysine. It binds to the pyrrolysine substrate. This protein has two functional domains. It has a C-terminus, which is the catalytic domain (PylSc) and has a Rossmann fold, which is a tertiary fold that binds to nucleotides. The other functional domain is the N-terminus that does the tRNA binding (PylSn). These two functional domains can work together to install two noncanonical amino acids at the same time.
== Biological relevance and broader implications ==
== Biological relevance and broader implications ==
== Important amino acids==
== Important amino acids==
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<scene name='95/954096/Amino_acids/1'>Amino Acids</scene> are an important part of the binding site.
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== Structural highlights ==
== Structural highlights ==
PylRS has two domains, an N-terminal and a C-terminal. The N-terminal is responsible for tRNA-binding, PylSn. The C-terminal is the catalytic domain, PylSc.
PylRS has two domains, an N-terminal and a C-terminal. The N-terminal is responsible for tRNA-binding, PylSn. The C-terminal is the catalytic domain, PylSc.
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The structure of PylRS appears symmetrical. There are many alpha helices as well as beta sheets and turns within.
 
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<scene name='95/954096/Pink_-_ligands/7'> Ligands within the structure are important for this protein</scene>
 
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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<scene name='95/954096/Pink_-_ligands/1'>Ligands highlighted pink</scene>
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</StructureSection>
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== References ==
== References ==
<references/>
<references/>

Revision as of 17:10, 27 April 2023

This Sandbox is Reserved from Mar 1 through Jun 1, 2023 for use in the course CHEM 351 Biochemistry taught by Bonnie_Hall at the Grand View University, Des Moines, USA. This reservation includes Sandbox Reserved 1796 through Sandbox Reserved 1811.
To get started:
  • Click the edit this page tab at the top. Save the page after each step, then edit it again.
  • show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
  • Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.

More help: Help:Editing

Pyrrolysyl-tRNA synthase (PylRS)

PylRS

Drag the structure with the mouse to rotate
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