Sandbox Reserved 1801
From Proteopedia
(Difference between revisions)
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== Function of your protein == | == Function of your protein == | ||
- | + | The function of the protein LDMS is to play a large role in Staphylococcal sulfur amino acid metabolism. On the image, you can see the backbone of the structure, (faintly colored), the amino acids, (in the center and brightly colored), and the ligands ADP and other ions floating around the molecule. LdmS commonly exists in an open state with the P-loop and N-loop disordered. | |
== Biological relevance and broader implications == | == Biological relevance and broader implications == | ||
- | The | + | The protein seems to play an important role in the bacteria Staphylococcus aureus. Scientist are trying to understand the process better to manipulate its metabolism and create better antibiotics The protein seems to mostly be active in gram-positive bacteria |
== Important amino acids== | == Important amino acids== | ||
<scene name='95/954098/Amino_acids_300-304/1'>Amino Acids 300-304</scene> are an important part of the drug binding site <ref>35988643</ref>. | <scene name='95/954098/Amino_acids_300-304/1'>Amino Acids 300-304</scene> are an important part of the drug binding site <ref>35988643</ref>. |
Current revision
This Sandbox is Reserved from Mar 1 through Jun 1, 2023 for use in the course CHEM 351 Biochemistry taught by Bonnie_Hall at the Grand View University, Des Moines, USA. This reservation includes Sandbox Reserved 1796 through Sandbox Reserved 1811. |
To get started:
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LDMS protein structure (maybe something like 'Structure')
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ 35988643