This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4y7f
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='4y7f' size='340' side='right'caption='[[4y7f]], [[Resolution|resolution]] 3.23Å' scene=''> | <StructureSection load='4y7f' size='340' side='right'caption='[[4y7f]], [[Resolution|resolution]] 3.23Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4y7f]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4y7f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y7F FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=48X:3-(PHOSPHONOOXY)PROPANOIC+ACID'>48X</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=48X:3-(PHOSPHONOOXY)PROPANOIC+ACID'>48X</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y7f OCA], [https://pdbe.org/4y7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y7f RCSB], [https://www.ebi.ac.uk/pdbsum/4y7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y7f ProSAT]</span></td></tr> | |
| - | + | ||
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/GPGS_MYCTU GPGS_MYCTU] Involved in the biosynthesis of methylglucose lipopolysaccharides (MGLPs). Catalyzes the condensation of NDP-glucose and 3-phospho-glycerate (3-PGA) to yield glucosyl-3-phosphoglycerate (GPG).<ref>PMID:22637481</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 25: | Line 22: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Glucosyl-3-phosphoglycerate synthase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | [[Category: Albesa-Jove | + | [[Category: Albesa-Jove D]] |
| - | [[Category: Cifuente | + | [[Category: Cifuente JO]] |
| - | [[Category: Comino | + | [[Category: Comino N]] |
| - | [[Category: Guerin | + | [[Category: Guerin ME]] |
| - | [[Category: Rodrigo-Unzueta | + | [[Category: Rodrigo-Unzueta A]] |
| - | [[Category: Sancho-Vaello | + | [[Category: Sancho-Vaello E]] |
| - | [[Category: Urresti | + | [[Category: Urresti S]] |
| - | + | ||
Revision as of 08:01, 3 May 2023
Crystal structure of glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis in complex with Mn2+, uridine-diphosphate-glucose (UDP-Glc) and 3-(phosphonooxy)propanoic acid (PPA) - GpgS Mn2+ UDP-Glc PPA
| |||||||||||
