4yko

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<StructureSection load='4yko' size='340' side='right'caption='[[4yko]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
<StructureSection load='4yko' size='340' side='right'caption='[[4yko]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4yko]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YKO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YKO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4yko]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YKO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YKO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yfp|4yfp]], [[4yfr|4yfr]], [[4yfq|4yfq]], [[4i9s|4i9s]], [[2g7b|2g7b]], [[4ruu|4ruu]], [[4eej|4eej]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yko OCA], [https://pdbe.org/4yko PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yko RCSB], [https://www.ebi.ac.uk/pdbsum/4yko PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yko ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRABP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yko OCA], [http://pdbe.org/4yko PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yko RCSB], [http://www.ebi.ac.uk/pdbsum/4yko PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yko ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN]] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
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[https://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Geiger, J]]
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[[Category: Geiger J]]
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[[Category: Nosrati, M]]
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[[Category: Nosrati M]]
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[[Category: Photoswitchable protein]]
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[[Category: Protein engineering]]
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[[Category: Retinal iminium pka change by isomerization]]
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[[Category: Retinal isomerization]]
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[[Category: Retinal psb]]
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[[Category: Rhodopsin mimic]]
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[[Category: Transport protein]]
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Revision as of 08:17, 3 May 2023

Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y:A32Y:F3Q mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 1.58 angstrom resolution

PDB ID 4yko

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OCA

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