This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4yl3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='4yl3' size='340' side='right'caption='[[4yl3]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
<StructureSection load='4yl3' size='340' side='right'caption='[[4yl3]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4yl3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YL3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YL3 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4yl3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YL3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YL3 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4U9:5-[4-BROMO-2-(2-CHLORO-6-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]-2-{[4-(TRIFLUOROMETHYL)PHENYL]ETHYNYL}PYRIDINE'>4U9</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4U9:5-[4-BROMO-2-(2-CHLORO-6-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]-2-{[4-(TRIFLUOROMETHYL)PHENYL]ETHYNYL}PYRIDINE'>4U9</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yk5|4yk5]], [[4yl0|4yl0]], [[4yl1|4yl1]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yl3 OCA], [https://pdbe.org/4yl3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yl3 RCSB], [https://www.ebi.ac.uk/pdbsum/4yl3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yl3 ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTGES, MGST1L1, MPGES1, PGES, PIG12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Prostaglandin-E_synthase Prostaglandin-E synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.99.3 5.3.99.3] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yl3 OCA], [http://pdbe.org/4yl3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yl3 RCSB], [http://www.ebi.ac.uk/pdbsum/4yl3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yl3 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/PTGES_HUMAN PTGES_HUMAN]] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).<ref>PMID:18682561</ref>
+
[https://www.uniprot.org/uniprot/PTGES_HUMAN PTGES_HUMAN] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).<ref>PMID:18682561</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 28: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Prostaglandin-E synthase]]
+
[[Category: Antonysamy S]]
-
[[Category: Antonysamy, S]]
+
[[Category: Fisher MJ]]
-
[[Category: Fisher, M J]]
+
[[Category: Kuklish SL]]
-
[[Category: Kuklish, S L]]
+
[[Category: Luz JG]]
-
[[Category: Luz, J G]]
+
-
[[Category: Inflammation]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Isomerase-isomerase inhibitor complex]]
+
-
[[Category: Prostaglandin]]
+

Revision as of 08:17, 3 May 2023

Crystal Structures of mPGES-1 Inhibitor Complexes

PDB ID 4yl3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4yl3"
Personal tools